Curriculum Vitae - David Lo

Distinguished Professor                                Adjunct Member, Division of Developmental Immunology

Division of Biomedical Sciences                   La Jolla Institute for Allergy and Immunology

University of California, Riverside               9420 Athena Circle

Riverside, CA 92521                                     La Jolla, CA 92037

Training and Experience:

Postdoctoral training, July 1986 - November 1989. Research developing transgenic mouse models for the study of induction and maintenance of immunological tolerance to tissue specific antigens. Advisor: Dr. Ralph L. Brinster, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA

Ph.D., 1986. University of Pennsylvania, Philadelphia, PA. Graduate training: Studies on the role of the thymus stroma in determining T lymphocyte self tolerance and the imprinting of T lymphocyte MHC restricted specificity. Advisor: Dr. Jonathan Sprent.

M.D., 1986. University of Pennsylvania, Philadelphia, PA

B.A., Biology, 1980. Haverford College, Haverford, PA

Selected publications (more than 120 papers)

1.       Carson, M.J., and Lo, D., Perspective is everything: an irreverent discussion of CNS-immune system interactions as viewed from different scientific traditions. Brain, Behavior, and Immunity, 21:367-73, 2006.

2.       Li, C.R, Santoso, S., and Lo, D., Quantitative analysis of T cell homeostatic proliferation. Cell. Immunol., 250: 40-54, 2007.

3.       Lo, D., Tynan, W., Dickerson, J., Scharf, M., Cooper, J., Byrne, D., Brayden, D., Higgins, L., Evans, C., and O’Mahony, D.J., Cell culture modeling of specialized tissue: Identification of genes expressed specifically by Follicle Associated Epithelium of Peyer’s Patch by expression profiling of Caco-2/Raji co-cultures. Intl. Immunol. 16:91-99, 2004.

4.       Goldfine, A.B., Crunkhorn, S., Costello, M., Gami, H., Landaker, E.J., Niinobe, M., Yoshikawa, K., Lo, D., Warren, A., Jimenez-Chillaron, J., and Patti, M.E., Necdin and E2F-4 are targets  of rosiglitazone therapy in diabetic human adipose and muscle tissues. Diabetes, 55:640-650, 2006.

5.       Carson, M.J., Thrash, J.C., Lo, D., Analysis of microglial gene expression: Toward targeted therapies for CNS neurodegenerative and autoimmune disease. Amer. J. Pharmacogenomics 4:321-30, 2004.

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