生理学与病理生理学系及北大糖尿病中心学术活动通知

题目：Serum, glucocorticoid reguated kinase?1 (SGK-1) and remodeling

讲演人： 杜杰教授 博士生导师

教育部长 江特聘教授 , 国家自然科学基金杰出青年

首都医科大学及北京市心肺血管研究所

时间：4.17日中午12点整

地点：生理楼三楼会议室

 

申请者近年的主要论著目录

1．  Ueda J, Starr ME, Takahashi H, Du J, Chang L, Crapo JD, Evers BM, Saito H.  Decreased pulmonary extracellular superoxide dismutase during systemic inflammation. Free Radical Biology & Medicine 2008 45(6):897-904

2．  Wang X, Hu Z, Du J, Klein J. Cardiac Muscle Protein Catabolism in Diabetes Mellitus: Activation of the Ubiquitin-Proteasome System by Insulin Deficiency Endocrinology 2008 149(11):5384-90

3．  Wang XH, Zhang L, LeDoux JM, Hu J, Mitch WE and Du J   Caspase-3 Cleaves Specific 19S Proteasome Regulatory Subunits in Skeletal Muscle Stimulating Proteasome Activity. Proc. Nat. Acad. Sci. 2009. (in revision)

4．  Hu Z, Du J and Mitch WE A Two Hit Mechanism, Endogenous Glucocorticoids and Impaired Insulin Signaling, Contributes to Muscle Wasting in Pathophysiological Conditions. Cell Metabolism 2009 (in revision).

5．  Zhang LP, Du J, Delafontaine and Mitch WE. Muscle wasting induced by excess angiotensin II involves responses from liver and muscle with synergy between IL-6 and serum amyloid A.  J Am Soc Nephrol. 2009 (Accepted).

6．  Garcia GE, Troung LD, Li P, Zhang P, Du J, Chen JF, Feng L. Adenosine A 2A recep tor activation and macrophage-mediated experimental glomerulonephritis. FASEB J. 2008 22:445-54.

7．  Zhu Q, Tang J, Youn H, Awfik O, Erranova P, Du J, Raynal P, Thrasher P, and Li B. Phosphoinositide 3-OH Kinase p110b is Essential for Androgen Receptor Transactivation and Tumor Growth in Prostate Cancer. Oncogene, 2008 27(33):4569-79.

8．  Cheng JZ, Du J Mechanical Stretch Simulates Proliferation of Venous Smooth Muscle Cells through Activation of the Insulin-like Growth Fac tor-1 Recep tor. Arteriosclerosis, Thrombosis, Vasc. Biol . 2007 27(8):1744-51

9．  Cheng J, Zhang J, Merched A, Zhang L, Zhang P, Troung L Boriek AM,  Du J Mechanical stretch suppresses Ox-LDL-induced apop tosis in vascular smooth muscle cells by upregulating integrin alphavbeta 3 and stabilization of PINCH-1. J. Biol. Chem. 2007 282(47):34268-75

10．            Cheng JZ, Cui RW, Chen C, Du J. Oxidized Low-density Lipoprotein Stimulates p53-dependent Activation of Pro-apop totic Bax Leading to Apop tosis of Differentiated Endothelial Progeni tor Cells  Endocrinology 148 (5): 2085-2094; 2007